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Shen, Le
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Item TypeName
Concept Tight Junctions
Academic Article A porous defense: the leaky epithelial barrier in intestinal disease.
Academic Article Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis.
Academic Article Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed.
Academic Article Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure.
Academic Article Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions.
Academic Article Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity.
Academic Article Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo.
Academic Article Tight junction pore and leak pathways: a dynamic duo.
Academic Article Dynamic migration of ?d intraepithelial lymphocytes requires occludin.
Academic Article The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state.
Academic Article Mechanisms and functional implications of intestinal barrier defects.
Academic Article Tight junctions on the move: molecular mechanisms for epithelial barrier regulation.
Academic Article The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding.
Academic Article LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms.
Academic Article Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.
Academic Article Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function.
Academic Article MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function.
Academic Article TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.
Academic Article The role of molecular remodeling in differential regulation of tight junction permeability.
Academic Article Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux.
Academic Article Claudin-2-dependent paracellular channels are dynamically gated.
Academic Article IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance.
Academic Article Microtubules are required for efficient epithelial tight junction homeostasis and restoration.
Academic Article Computational Modeling of Claudin Structure and Function.
Academic Article Cerebral Cavernous Malformation Proteins in Barrier Maintenance and Regulation.
Academic Article Idiopathic pulmonary fibrosis is associated with tight junction protein alterations.
Academic Article ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
Academic Article The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo.
Academic Article Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase-3 Expression.
Academic Article Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice.
Academic Article Molecular mechanism of claudin-15 strand flexibility: A computational study.
Concept Zonula Occludens-1 Protein
Concept Zonula Occludens-2 Protein
Concept Tight Junction Proteins
Grant Contribution of occludin to intestinal homeostasis and disease
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